TY - JOUR T1 - [Adult Kawasaki disease: A diagnostic case report]. AU - Leclerc,Valentine, AU - Danset,Marie, AU - Durupt,François, AU - Berset-de-Vaufleury,Jean, AU - Tabary,Axel, AU - Tantot,Juliet, AU - Trecourt,Alexis, AU - Harou,Olivier, AU - Balme,Brigitte, AU - Donzel,Marie, Y1 - 2026/01/27/ PY - 2025/07/29/received PY - 2025/10/27/revised PY - 2026/01/07/accepted PY - 2026/5/5/medline PY - 2026/1/29/pubmed PY - 2026/1/28/entrez KW - Adult KW - Adulte KW - Biopsie cutanée KW - Granuloma KW - Granulomes KW - Kawasaki disease KW - Maladie de Kawasaki KW - Skin biopsy KW - Vasculite KW - Vasculitis SP - 275 EP - 279 JF - Annales de pathologie JO - Ann Pathol VL - 46 IS - 3 N2 - Kawasaki disease (KD) is an acute systemic vasculitis mainly affecting medium-size blood vessels and primarily affecting children under five years old. The typical clinical presentation associates fever, skin rash, mucous membrane abnormalities, and lymphadenopathies. Occurrence in adults is rare, with fewer than 100 cases reported and limited histological descriptions available, particularly regarding the skin. We report herein the case of a 22-year-old man hospitalized for fever, odynophagia, and aphagia since five days. Clinical examination revealed enanthem with palatal ulcerations, maculopapular lesions with fine scaling on the limbs and extremities, painful scrotal ulcerations, bilateral non-exudative conjunctivitis, and bilateral lymphadenopathy. Laboratory tests showed an isolated inflammatory syndrome. Skin biopsy revealed lichenoid epidermal changes along with a polymorphic dermal inflammatory infiltrate exhibiting a granulomatous pattern and comprising abundant lymphocytes, accompanied by vascular changes. The diagnosis of KD was established by integrating clinical and histological data. Early recognition of this disease in adults is essential to prevent chronic complications; this report aims to describe its potential histological features. SN - 0242-6498 UR - https://www.unboundmedicine.com/prime/citation/41605769/[Adult_Kawasaki_disease:_A_diagnostic_case_report]. DB - PRIME DP - Unbound Medicine ER -